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Las evidencias arqueológicas del uso del peyote se remontan a más de 5.000 a¿nos.
Throughout history, numerous societies have isolated substances with hallucinogenic properties from fungus, plant, and animal sources.
From an ethnobotanist's and anthropologist's viewpoint, the American continents provide excellent opportunities for studying a wide array of natural hallucinogens.
The diverse civilisations that flourished in Mesoamerica displayed great knowledge and skill in their use of numerous hallucinogens.
Archaeological, ethnohistorical, and ethnographic evidence show that throughout history, pre-Columbian Mesoamerican cultures used hallucinogenic substances in magical, therapeutic, and religious rituals.
These substances are considered entheogens since they were used to promote mysticism and communication with divine powers.
The purpose of using these substances was to enter a trance and achieve greater enlightenment and open-mindedness.
The altered state of consciousness the user aimed to reach was characterised by temporal and spatial disorientation, a sensation of ecstasy and inner peace, hallucinations of vivid colours, tendency towards introspection, and an impression of being one with nature and with the gods.
Mesoamerican myths and religions emphasise the role of the priest or shaman as a mediator between the physical and the spiritual worlds, and this situation promoted the use of entheogens in religious ceremonies and prophecy.
Shamans, intermediaries between the natural and supernatural realms, would consume numerous psychoactive substances to undertake their shamanic journeys.
Ritual enemas and other psychoactive substances were also used to induce states of trance.
Olmec, Zapotec, Maya and Aztec used peyote, hallucinogenic mushrooms (teonanacatl: were used for their psychoactive effects.
Mushroom stones dating from 3000 BC have been found in ritual contexts in Mesoamerica.